Principal’s Profile

Biographical Sketch of the Principal
Madhumita Manna   M.Phil. Ph.D
AWARDS AND SCHOLARSHIP:
First Class First in B.Sc Hons Exam. and Jubilee Post Graduate (Merit) prize, 1985 from Calcutta University
First Class Third in M.Sc (Zoology) Exam. from Calcutta University
National Scholarship in B.Sc. Examination
RESEARCH:
Ph.D degree from Jadavpur University : Under the guidance of late Prof. Amar Nath Bhaduri, Bhatnagar awardee and the then Director, Indian Institute of chemical Biology, Kolkata
Principal Investigator/Supervisor in Research projects: 7

Sl. No.

Title of Project

Funding Agency

Amount

1.

Direct diagnosis and characterization of the causal agents of Kala-azar from North East and Eastern region of India by molecular methods.
Acting as Principal Investigator from Collaborating Institute I

Department of Biotechnology (DBT), Govt. of India

[DBT TWINNING Programme for NE]

Collaborating Institutes:
1.Gauhati Medical College, Assam
2. Calcutta National Medical College, Kolkata

Total project Rs. 99.98 Lakhs (L)
2013-2016

2.

Influences of trace elements in the immune functions in visceral leishmaniasis and post kala-azar dermal leishmaniasis of India 
Principal Investigator

UGC-DAE Consortium for Scientific Research, Kolkata Centre

Rs.6.5 L [approx]

   2009-2013

3.

An Approach to develop an immunotherapeutic and prophylactic agent by attenuated  leishmania parasite Project guide

CSIR SRF project guidance
[Ms. Sanchita Datta]

Rs.9.739 L
2011-2014

4.

Application of modern taxonomical methods for characterization of drug sensitive and drug unresponsive isolates of Kala-azar in India.
 Project guide

CSIR SRF project guidance
[Ms. Supriya Khanra]

Rs.8.721 L
2013-2015

5.

Radiation and molecular immunology: Understanding the mechanism of protection against leishmania protection using radioattenuated leishmania parasites
Principal Investigator

UGC DAE Consortium for Scientific Research, Kolkata Centre

Rs. 9.10 L (approx)
2005-2010

6.

Genome Analysis and development of genetic markers of the clinical isolates of Indian visceral leishmaniasis (Kala-azar) and post kala-azar dermal leishmaniasis with special emphasis on drug unresponsive cases of Kala-azar
Principal Investigator

University Grant Commission

Rs. 9.929 L
2009-2012

7.

Molecular Taxonomic Analysis of clinical isolates of Indian Kala-azar Patients
Principal Investigator

University Grant Commission (minor)

Rs 0.85 L

IMPORTANT PUBLICATIONS

  1. Genetic markers for antimony resistant clinical isolates differentiation from Indian Kala-azar. Supriya Khanra, Nibedeeta Rani Sarraf,Shantanabha Das, Anjan Kumar Das, Syamal Roy, Madhumita Manna. Acta Tropica. 164, 177-184, 2016. (Impact factor 2.380).
  2. Molecular identification of an old clinical isolate of Indian Kala-azar. Journal of Parasitic Diseases. Madhumita Manna, Supriya Khanra, 2016.  doi:10.​1007/​s12639-016-0799-9.
  3. Therapy with radio-attenuated vaccine in experimental murine visceral leishmaniasis showed enhanced T cell and iNOS levels, suppressed TGF- βproduction with higher expression of some signaling molecules. Sanchita data, Syamal Roy and Madhumita Manna.Brazilian Journal of Infectious Diseases (Elsevier), 2015. (Impact factor1.31).
  4. Evaluation of S.C. route of immunization by homologous radio attenuated live vaccine in experimental     murine visceral leishmaniasis. Sanchita data, Syamal Roy, Anindita Chakraborty and Madhumita Manna. Journal of Parasitic Diseases (Springer), 2014.DOI: 10.1007/s12639-014-0522-7.
  5. Correlation of Obesity and the Novel Adipocytokines, Leptin and Adiponectin with Insulin Resistance in Type- 2 Diabetes Mellitus. Piyali Das, Subir Kumar Bandyopadhyay, Subhradev Biswas, Gorachand Bhattacharya, Madhumita Manna. Bangladesh Journal of Physiology and Pharmacology, 2014; 30 (1):29-32.
  6. Cytokine Release Analyses of SSG Resistant Recent Clinical Isolate of Kala-azar Identified As Leishmania tropica. Supriya Khanra, Anjan Kumar Das, Rupkatha Mukhopadhyay, Syamal Roy and Madhumita Manna. Perspective in Cytology and Genetics. 2013.
  7. Molecular Epidemiology of Indian Kala-azar. Madhumita Manna. Perspective in Cytology and Genetics. 2013.
  8. Further Characterization of Recent Clinical Isolates of Indian Kala-azar. Supriya Khanra, Anjan Kumar Das, Suresh Kumarand Madhumita Manna. Proceedings of the National Conference of Challenges in Biodiversity Conservation and Resource Management, February, 2013.
  9. RFLPs of ITS, ITS-1, hsp70 and sequencing of ITS-1 of some recent clinical isolates from kala-azar patients of India and Bangladesh revealed heterogeneity in parasite population structures. Supriya Khanra, Sanchita Dutta, Dinesh Mondal, Partha Saha, Subir Kumar Bandopadhyay Syamal Roy and Madhumita Manna. Acta Tropica (Elsevier), 2012,124 (3), 229-234[Impact factor 2.787]
  10. Therapeutic Immunization with radio attenuated leishmania parasites through i.m route revealed protection against the experimental murine visceral leishmaniasis. Sanchita Datta, Madhumita Manna, Supriya Khanra, Moumita Ghosh, Radhaballav Bhar, Anindita Chakraborty, Syamal Roy. Parasitology Research (Springer), 2012, Jul. 111(1), 361-369. [Impact factor 2.852]
  11. Radioattenuated leishmania parasites as immunoprophylactic agent against Indian visceral leishmaniasis. Sanchita Datta, Rupchand Adak, Priyanka Chakraborty, Arun Halder, Surajit Bhattacharya, Anindita Chakraborty, Syamal Roy and Madhumita Manna. Experimental Parasitology (Elsevier), 2012, Jan 130 (1), 39-47 [Impact factor 2.154]
  12. Analysis of Lactate Dehydrogenase and Malate Dehydrogenase enzyme profiles of some Indian major carps of East Calcutta Wetland by Cellulose Acetate Electrophoresis.Madhumita Manna and Priyanka Chakraborty. Journal of Environmental Biology, 33 (4), 2012. [ISSN no. 0254-8704] [Impact factor 0.68]
  13. Characterization of the recent clinical isolates of Indian Kala-Azar patients by RAPD-PCR method. Supriya Khanra,Subir K Bandopadhyay, Priyanka Chakraborty, Sanchita Datta, Dinesh Mondal,   Mitali     Chatterjee, Kshudiram Naskar, Syamal Roy and Madhumita Manna. Journal of Parasitic Diseases (Springer), 2011, 35, 116-122.
  14. RAPD patterns in different species of Drosophila. Arpita Rakshit, Madhumita Manna and Rabindra Nath Chatterjee. Perspective in Cytology and Genetics. 2011, Volume 15, 47-54.
  15. Immunotherapeutic Role of Radio Attenuated Leishmania Parasites in Experimental Murine Leishmaniasis. Datta S, Naskar K, Chakraborty A, Manna M. Medimond International Proceedings [Thomson Reuters], ICOPA XII, 2010.
  16. Radiation Induced Effects on Viability and Antioxidant Enzymes of Crustaceans from    Different Habitats. D. Mukherjee, M. Manna, S.Selveraj, S.Bhattacharyya, S. Homechoudhury, and A. Chakraborty.  Journal of Environmental Biology, Vol 31, 251-254, 2010. ISSN no. 0254-8704[Impact factor 0.64]
  17. MLEE and RAPD-PCR of the clinical isolates of Kala-azar patients of India suggest Leishmania donovani is the only causal agent of Indian Kala -azar. Madhumita Manna, Hemanta Kumar Majumder, Shyam Sundar and Amar Nath Bhaduri. Medical Science Monitor, USA,Vol 11(7), 220-227, 2005.[Impact factor 1.36]
  18. Chemical unresponsiveness to Kala-azar: Breaking the Barrier. Madhumita Manna, Kalipada Kar, Hemanta Majumder & Amar Nath Bhaduri. Round Table Conference Series-Kala-azar, Number 5, 53-58, 1999. Editors: Dr. Sushma Gupta and O.P. Sood. Ranbaxy Science Foundation, New Delhi, India.
  19. Recent Kala-azar cases in India: Isozyme profiles of Leishmania parasites. Mitali Chatterjee, Madhumita Manna, A.N.Bhaduri & Dwijen Sarker. Indian Journal of Medical Research 102, 165-172, 1995[Impact factor 2.061]
  20. Antileishmanial activities of some antidepressant drugs. Paramita sarkar and Madhumita Manna. Journal of Zoological Sciences, e-ISSN 2321-6190, p ISSN 2347-2294, 2015

INTERNATIONAL CONFERENCES/ SYMPOSIUM /WORKSHOP ATTENDED AND PAPERS PRESENTED: 10
Countries visited: Italy, Australia, Bangladesh
REVIEWER of International Journals: 6

RESOURCE PERSON:

  1. UGC DAE pre Ph.D Course work
  2. M.Phil Courses Kalyani Univ. and Univ. of Calcutta

M.PHIL AWARDED UNDER HER GUIDANCE: 3
PH.D AWARDED : 2
1. Dr. Sanchita Datta:   Awarded degree on 2014 from Jadavpur Unversity. She is now working as D.S. Kothary Post doctoral fellow in Dept. of Pharmacy, Jadavpur University
2. Dr. Supriya Khanra :  Awarded degree on 2015 from Jadavpur Unversity. She is now working as Research Associate in Saha Institute of Nuclear Physics, Kolkata
  PH. D REGISTERED: 3

  1. Sangita Lahiry under Jadavpur University
  2. Nibedeeta Rani Sarraf under Jadavpur University
  3. Dr. Piyali Das under West Bengal Health Science Unversity

Achievement of the Ph.D students:
Sangita Lahiry was awarded Best Oral award in International Conference on ‘The Green Planet: Past, Present and Future’ in 2016
Supriya Khanra received second Best Poster award in 15th AICCG, 2011.

Membership

  1. Life Member, All India Cytology and Genetics, India.
  2. Life member, Zoological Society, Kolkata, India.
  3. Life member, Indian Science News Association
  4. International Society for Vaccines, USA

GENBANK ACCESSION:
JQ229828 ,JQ517279 , KP780082, KP780081, KP780083, KP780085, KP780084, KP780088,
                               KP780087, KP780089, KP780086, KM982539, KJ465106, KJ465107,
                               KJ465108, KJ465104, KJ018017, KJ465105, KF500031, KF673344,
                               KP246847, KF673345, KM982538  and many [ITS-1 sequences of Leishmania donovani
                                isolates collected from Kala-azar or Post Kala-azar Dermal Leishmaniasis
                                patients were submitted and accepted  in NCBI,  Genbank, USA] 
SOCIAL ACTIVITIES 

  1. Member of NSS, Bethune College unit, Bethune College, Kolkata and Convener, NSS Girls’ Unit, Barasat  Govt. College, Kolkata
  2. Regular blood donor